For USPS shipments, after you have have purchased your shipping and printed your label, you can drop off your packages at your nearest post office or postal box.
For UPS shipments, after you have purchased your shipping and printed your label, you can drop off your packages at any one of nearly 4,400 locations of The UPS Store or hand your package to any UPS driver at no additional charge. For an additional fee, you can arrange for a pickup through http://www.ups.com/ or 1.800.PICK.UPS